Taking too much acetaminophen with codeine may cause liver problems. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately. Low blood pressure: Codeine may cause low blood pressure or make low blood pressure worse. If you experience severe dizziness, especially when standing from a lying or sitting position, contact your doctor.
Other medical conditions: If you are about to undergo surgery of the biliary tract, approach taking codeine with caution, as it may worsen your condition. Codeine will worsen the effects of acute alcohol intoxication and delirium tremens. As well, if you have low thyroid hypothyroidism , Addison's disease, benign prostatic hypertrophy enlarged prostate , gallbladder disease, urethral stricture, decreased function of the adrenal glands, or porphyria, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Ultra-rapid codeine metabolizers: Some people process codeine faster and more completely than others due to a genetic variation. This can result in higher-than-expected drug levels in the body, which may result in overdose symptoms and serious or life-threatening effects on breathing.
If you are known to be a rapid metabolizer of codeine you should avoid using this medication. Worsening symptoms: If redness or swelling occurs in the area of pain, if symptoms do not improve or they worsen, or if new symptoms develop e.
These may be signs of other conditions that require medical attention. Seizures: This medication may cause seizures. Seizures are more likely to occur when higher doses of this medication are taken. If you have a history of epilepsy or medical conditions that increase the risk of seizures, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Serotonin syndrome: Although rare, severe reactions are possible when codeine is combined with other medications that act on serotonin, such as tricyclic antidepressants and serotonin reuptake inhibitors medications used to treat depression. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, or changes in mental state including delirium and agitation. Coma and death are possible. If you are taking antidepressants, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately. Infants born to mothers who have been taking codeine for long periods of time may experience dangerous withdrawal symptoms at birth. Breast-feeding: Acetaminophen, codeine, and caffeine pass into breast milk.
Some of the codeine dose is converted into morphine by the body, once it has been taken. For some people, this change happens much faster than for others. If this happens to a nursing mother, the baby is at risk of receiving a morphine overdose through the breast milk. If you are breast-feeding and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children under 12 years old. Medications containing codeine should not be given to people under 18 years old for pain management after surgery to remove the tonsils and or adenoids. Non-prescription products containing codeine should not be used by people under 18 years old.
Recent evidence shows that young people who use opioids, including codeine, may be more likely to have problems with the misuse of medications and other substances later in life. Seniors: Seniors who take this medication may be more likely to experience side effects or worsening of preexisting medical conditions.
If you are taking any of these medications, speak with your doctor or pharmacist. People with a history of past or current substance use problems may be at greater risk of developing abuse or addiction while taking this medication.
Abuse is not a problem with people who require this medication for pain relief. Talk to your doctor if you have any concerns about dependence. You should avoid such activities until you are certain this medication does not have this effect on you. Head injury: People with head injuries or increased pressure in the head may have a higher risk of experiencing side effects breathing problems or worsening of their condition while taking this medication.
If you have had a recent head injury, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Kidney function: If you have severely reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver function: If you have severely reduced liver function or liver disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Other medical conditions: If you have hypothyroidism, Addison's disease, enlarged prostate BPH; benign prostatic hypertrophy , or narrowing of the urethra, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Seizures: This medication may cause seizures, especially when higher doses are used or when taken with other medications that may increase the risk of seizures such as:. The risk of seizures is also higher for people with epilepsy, a history of seizures, or who are at risk of seizures e. Pregnancy: Dependence and withdrawal signs have been reported in newborns whose mothers took medications such as acetaminophen - codeine regularly during pregnancy. This medication should not be used during pregnancy unless the benefits outweigh the risks.
If you become pregnant while taking this medication, contact your doctor immediately. Breast-feeding: Acetaminophen and codeine pass into breast milk.
Babies who are breast-fed by mothers who metabolize codeine very quickly may be at increased risk for codeine overdose because there may be higher-than-expected levels of codeine in breast milk. The safety of this medication has not been established for use by breast-feeding mothers and is not recommended for use while breast-feeding. Children: The tablet and caplet form of this medication should not be given to children less than 12 years of age.
The liquid form of the medication should not be given to children under 2 years of age. If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:. An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed. Medications other than those listed above may interact with this medication.
Tell your doctor or prescriber about all prescription, over-the-counter non-prescription , and herbal medications you are taking. Also tell them about any supplements you take.
Both products contain the same active ingredient, mg of acetaminophen. Your first name and last initial will be displayed publicly to other users when you write a review or blog post ex.
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By clicking "Accept" below, you confirm that you have read, understand and accept our sites's Privacy Policy. Where to Buy. Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 4, mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: acetaminophen may cause severe skin reactions. This medication may be taken with or without food.
Consuming alcohol may intensify the effect of this product. It is therefore advisable to avoid consuming alcohol or alcohol-containing products while taking this medication. In addition to its desired action, this medication may cause some side effects, notably: it may cause drowsiness or dizziness -- use caution if driving; it may cause nausea and vomiting; it may cause constipation -- to prevent this, drink plenty of water or juice, and eat more dietary fibre.
Each person may react differently to a treatment. If you think this medication may be causing side effects including those described here, or others , talk to your doctor or pharmacist.
He or she can help you to determine whether or not the medication is the source of the problem. As with most medications, this product should be stored at room temperature. Store it in a secure location where it will not be exposed to excessive heat, moisture or direct sunlight.
Keep it out of reach of young children.
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